NSF Center for Aqueous
Supramolecular Chemistry

The NSF Center for Aqueous Supramolecular Chemistry (CASC) is supported by the Centers for Chemical Innovation (CCI) Program of the Division of Chemistry. The ability of custom-designed molecules to 1) selectively recognize and bind to negatively charged molecules (anions), 2) transport these anions across membranes and/or 3) enable chemical transformations to new products is an all-but-unmet challenge. This Center will overcome these challenges by synthesizing novel molecules that target two anions of particular importance to society: bicarbonate and perfluorooctanoic acid (PFOA). Carbon dioxide from greenhouse gas emissions resides predominantly in surface ocean waters as bicarbonate. PFOA is well recognized for its persistence and toxic effects in groundwater. The selective capture, transport and transformation of these two anions will foster numerous technological payoffs. Activities within this Center include the training of students in the commercialization of technology and the creation of custom Individual Development Plans for all incoming scholars. CASC will establish a summer undergraduate program that trains students to continue projects at their home institution, and will engage the public in hands-on activities at museums and science centers.